Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline United Airlines
Cheapest Month October
Cheapest Day of the Week Thursday
Cheapest Airline United Airlines

The cheapest airline(s) flying from Indianapolis to Knoxville is United Airlines.

  • American Airlines American Airlines
  • United Airlines United Airlines
  • Allegiant Air LLC Allegiant Air LLC
Cheapest Month October

Travel Period: June 2025 - May 2026

The cheapest month(s) to fly from Indianapolis to Knoxville is October.

  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
  • Jan 2026
  • Feb 2026
  • Mar 2026
  • Apr 2026
  • May 2026
Cheapest Day of the Week Thursday

The cheapest day(s) of the week to fly from Indianapolis to Knoxville is Thursday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Fri, 2 May, 2025

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      • Availability
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      • 05:40 IND
        10:05 TYS
        4Hrs, 25m 1 Stop (IAD)
      • INDIndianapolis Airport 05:40 - TYS 10:05 4h 25m 1 Stop (IAD) Washington
      • INDIndianapolis Airport 05:40
        IADWashington Dulles International Airport 08:20
      • IADWashington Dulles International Airport 07:21
        TYSKnoxville Airport 10:05
      • 4h 25m (59m)
      • 1 Stop IAD · Washington 59m
      • United Airlines (UA 6091)Embraer 175
        United Airlines (UA 4257)Embraer
      • United Airlines (UA 6091)
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      • 05:43 IND
        10:05 TYS
        4Hrs, 22m 1 Stop (IAD)
      • INDIndianapolis Airport 05:43 - TYS 10:05 4h 22m 1 Stop (IAD) Washington
      • INDIndianapolis Airport 05:43
        IADWashington Dulles International Airport 08:20
      • IADWashington Dulles International Airport 07:24
        TYSKnoxville Airport 10:05
      • 4h 22m (56m)
      • 1 Stop IAD · Washington 56m
      • United Airlines (UA 6091)Embraer 175
        United Airlines (UA 4257)Embraer
      • United Airlines (UA 6091)
        • -
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      • 06:00 IND
        10:15 TYS
        4Hrs, 15m 1 Stop (ORD)
      • INDIndianapolis Airport 06:00 - TYS 10:15 4h 15m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 06:00
        ORDChicago O'Hare International Airport 07:30
      • ORDChicago O'Hare International Airport 06:20
        TYSKnoxville Airport 10:15
      • 4h 15m (1h 10m)
      • 1 Stop ORD · Chicago 1h 10m
      • United Airlines (UA 3479)Embraer 175
        United Airlines (UA 5726)Canadair Regional Jet 550
      • United Airlines (UA 3479)
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      • 06:00 IND
        10:16 TYS
        4Hrs, 16m 1 Stop (ORD)
      • INDIndianapolis Airport 06:00 - TYS 10:16 4h 16m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 06:00
        ORDChicago O'Hare International Airport 07:30
      • ORDChicago O'Hare International Airport 06:20
        TYSKnoxville Airport 10:16
      • 4h 16m (1h 10m)
      • 1 Stop ORD · Chicago 1h 10m
      • United Airlines (UA 3479)Embraer 175
        United Airlines (UA 5726)Embraer 175
      • United Airlines (UA 3479)
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      • 06:10 IND
        10:28 TYS
        4Hrs, 18m 1 Stop (CLT)
      • INDIndianapolis Airport 06:10 - TYS 10:28 4h 18m 1 Stop (CLT) Charlotte
      • INDIndianapolis Airport 06:10
        CLTCharlotte Airport 09:05
      • CLTCharlotte Airport 07:53
        TYSKnoxville Airport 10:28
      • 4h 18m (1h 12m)
      • 1 Stop CLT · Charlotte 1h 12m
      • American Airlines (AA 2938)Boeing 737 800
        American Airlines (AA 5944)Er4 Embraer Rj145 Amazon
      • American Airlines (AA 2938)
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      • 09:00 IND
        13:22 TYS
        4Hrs, 22m 1 Stop (ORD)
      • INDIndianapolis Airport 09:00 - TYS 13:22 4h 22m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 09:00
        ORDChicago O'Hare International Airport 10:35
      • ORDChicago O'Hare International Airport 09:20
        TYSKnoxville Airport 13:22
      • 4h 22m (1h 15m)
      • 1 Stop ORD · Chicago 1h 15m
      • United Airlines (UA 3565)Embraer 175
        United Airlines (UA 4505)Canadair Regional Jet 550
      • United Airlines (UA 3565)
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      • 10:04 IND
        14:16 TYS
        4Hrs, 12m 1 Stop (CLT)
      • INDIndianapolis Airport 10:04 - TYS 14:16 4h 12m 1 Stop (CLT) Charlotte
      • INDIndianapolis Airport 10:04
        CLTCharlotte Airport 13:01
      • CLTCharlotte Airport 11:45
        TYSKnoxville Airport 14:16
      • 4h 12m (1h 16m)
      • 1 Stop CLT · Charlotte 1h 16m
      • American Airlines (AA 2062)Airbus
        American Airlines (AA 4169)Embraer Emb 175
      • American Airlines (AA 2062)
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      • 10:13 IND
        14:35 TYS
        4Hrs, 22m 1 Stop (IAD)
      • INDIndianapolis Airport 10:13 - TYS 14:35 4h 22m 1 Stop (IAD) Washington
      • INDIndianapolis Airport 10:13
        IADWashington Dulles International Airport 12:50
      • IADWashington Dulles International Airport 11:55
        TYSKnoxville Airport 14:35
      • 4h 22m (55m)
      • 1 Stop IAD · Washington 55m
      • United Airlines (UA 3709)Embraer 175
        United Airlines (UA 4282)Embraer
      • United Airlines (UA 3709)
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      • 10:43 IND
        14:34 TYS
        3Hrs, 51m 1 Stop (ORD)
      • INDIndianapolis Airport 10:43 - TYS 14:34 3h 51m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 10:43
        ORDChicago O'Hare International Airport 11:54
      • ORDChicago O'Hare International Airport 10:58
        TYSKnoxville Airport 14:34
      • 3h 51m (56m)
      • 1 Stop ORD · Chicago 56m
      • American Airlines (AA 2349)Airbus
        American Airlines (AA 5745)Er4 Embraer Rj145 Amazon
      • American Airlines (AA 2349)
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      • 10:43 IND
        14:34 TYS
        3Hrs, 51m 1 Stop (ORD)
      • INDIndianapolis Airport 10:43 - TYS 14:34 3h 51m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 10:43
        ORDChicago O'Hare International Airport 11:54
      • ORDChicago O'Hare International Airport 10:59
        TYSKnoxville Airport 14:34
      • 3h 51m (55m)
      • 1 Stop ORD · Chicago 55m
      • American Airlines (AA 3963)Embraer 170
        American Airlines (AA 5745)Er4 Embraer Rj145 Amazon
      • American Airlines (AA 3963)
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      • 10:49 IND
        15:40 TYS
        4Hrs, 51m 1 Stop (CLT)
      • INDIndianapolis Airport 10:49 - TYS 15:40 4h 51m 1 Stop (CLT) Charlotte
      • INDIndianapolis Airport 10:49
        CLTCharlotte Airport 14:30
      • CLTCharlotte Airport 12:30
        TYSKnoxville Airport 15:40
      • 4h 51m (2h)
      • 1 Stop CLT · Charlotte 2h
      • American Airlines (AA 2079)Boeing 737 800
        American Airlines (AA 5641)Canadair Regional
      • American Airlines (AA 2079)
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      • 10:49 IND
        14:24 TYS
        3Hrs, 35m 1 Stop (CLT)
      • INDIndianapolis Airport 10:49 - TYS 14:24 3h 35m 1 Stop (CLT) Charlotte
      • INDIndianapolis Airport 10:49
        CLTCharlotte Airport 13:11
      • CLTCharlotte Airport 12:30
        TYSKnoxville Airport 14:24
      • 3h 35m (41m)
      • 1 Stop CLT · Charlotte 41m
      • American Airlines (AA 2079)Boeing 737 800
        American Airlines (AA 5579)Canadair Regional
      • American Airlines (AA 2079)
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      • 12:09 IND
        15:40 TYS
        3Hrs, 31m 1 Stop (CLT)
      • INDIndianapolis Airport 12:09 - TYS 15:40 3h 31m 1 Stop (CLT) Charlotte
      • INDIndianapolis Airport 12:09
        CLTCharlotte Airport 14:30
      • CLTCharlotte Airport 13:50
        TYSKnoxville Airport 15:40
      • 3h 31m (40m)
      • 1 Stop CLT · Charlotte 40m
      • American Airlines (AA 2062)Airbus
        American Airlines (AA 5641)Canadair Regional
      • American Airlines (AA 2062)
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      • 12:49 IND
        16:54 TYS
        4Hrs, 05m 1 Stop (ORD)
      • INDIndianapolis Airport 12:49 - TYS 16:54 4h 05m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 12:49
        ORDChicago O'Hare International Airport 14:00
      • ORDChicago O'Hare International Airport 13:09
        TYSKnoxville Airport 16:54
      • 4h 05m (51m)
      • 1 Stop ORD · Chicago 51m
      • United Airlines (UA 3484)Embraer 175
        United Airlines (UA 5714)Embraer 175
      • United Airlines (UA 3484)
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      • 14:48 IND
        19:31 TYS
        4Hrs, 43m 1 Stop (IAD)
      • INDIndianapolis Airport 14:48 - TYS 19:31 4h 43m 1 Stop (IAD) Washington
      • INDIndianapolis Airport 14:48
        IADWashington Dulles International Airport 17:45
      • IADWashington Dulles International Airport 16:30
        TYSKnoxville Airport 19:31
      • 4h 43m (1h 15m)
      • 1 Stop IAD · Washington 1h 15m
      • United Airlines (UA 3530)Embraer 175
        United Airlines (UA 4914)Embraer
      • United Airlines (UA 3530)
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      • 15:45 IND
        19:14 TYS
        3Hrs, 29m 1 Stop (CLT)
      • INDIndianapolis Airport 15:45 - TYS 19:14 3h 29m 1 Stop (CLT) Charlotte
      • INDIndianapolis Airport 15:45
        CLTCharlotte Airport 18:13
      • CLTCharlotte Airport 17:29
        TYSKnoxville Airport 19:14
      • 3h 29m (44m)
      • 1 Stop CLT · Charlotte 44m
      • American Airlines (AA 1589)Boeing 737 800
        American Airlines (AA 2015)Airbus
      • American Airlines (AA 1589)
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      • 15:45 IND
        19:56 TYS
        4Hrs, 11m 1 Stop (CLT)
      • INDIndianapolis Airport 15:45 - TYS 19:56 4h 11m 1 Stop (CLT) Charlotte
      • INDIndianapolis Airport 15:45
        CLTCharlotte Airport 18:40
      • CLTCharlotte Airport 17:29
        TYSKnoxville Airport 19:56
      • 4h 11m (1h 11m)
      • 1 Stop CLT · Charlotte 1h 11m
      • American Airlines (AA 1589)Boeing 737 800
        American Airlines (AA 5991)Er4 Embraer Rj145 Amazon
      • American Airlines (AA 1589)
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      • 15:46 IND
        19:14 TYS
        3Hrs, 28m 1 Stop (CLT)
      • INDIndianapolis Airport 15:46 - TYS 19:14 3h 28m 1 Stop (CLT) Charlotte
      • INDIndianapolis Airport 15:46
        CLTCharlotte Airport 18:13
      • CLTCharlotte Airport 17:30
        TYSKnoxville Airport 19:14
      • 3h 28m (43m)
      • 1 Stop CLT · Charlotte 43m
      • American Airlines (AA 1589)Boeing 737 800
        American Airlines (AA 2015)Airbus
      • American Airlines (AA 1589)
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      • 15:47 IND
        19:25 TYS
        3Hrs, 38m 1 Stop (ORD)
      • INDIndianapolis Airport 15:47 - TYS 19:25 3h 38m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 15:47
        ORDChicago O'Hare International Airport 16:44
      • ORDChicago O'Hare International Airport 16:05
        TYSKnoxville Airport 19:25
      • 3h 38m (39m)
      • 1 Stop ORD · Chicago 39m
      • American Airlines (AA 3635)Embraer Emb 175
        American Airlines (AA 5732)Er4 Embraer Rj145 Amazon
      • American Airlines (AA 3635)
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      • 15:47 IND
        19:25 TYS
        3Hrs, 38m 1 Stop (ORD)
      • INDIndianapolis Airport 15:47 - TYS 19:25 3h 38m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 15:47
        ORDChicago O'Hare International Airport 16:44
      • ORDChicago O'Hare International Airport 16:05
        TYSKnoxville Airport 19:25
      • 3h 38m (39m)
      • 1 Stop ORD · Chicago 39m
      • American Airlines (AA 3433)Embraer 170
        American Airlines (AA 5732)Er4 Embraer Rj145 Amazon
      • American Airlines (AA 3433)
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      • 18:18 IND
        23:07 TYS
        4Hrs, 49m 1 Stop (ORD)
      • INDIndianapolis Airport 18:18 - TYS 23:07 4h 49m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 18:18
        ORDChicago O'Hare International Airport 20:20
      • ORDChicago O'Hare International Airport 18:35
        TYSKnoxville Airport 23:07
      • 4h 49m (1h 45m)
      • 1 Stop ORD · Chicago 1h 45m
      • United Airlines (UA 767)Airbus
        United Airlines (UA 1069)Boeing 737 900
      • United Airlines (UA 767)
        • -
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        • -
      • 18:18 IND
        22:45 TYS
        4Hrs, 27m 1 Stop (ORD)
      • INDIndianapolis Airport 18:18 - TYS 22:45 4h 27m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 18:18
        ORDChicago O'Hare International Airport 19:58
      • ORDChicago O'Hare International Airport 18:35
        TYSKnoxville Airport 22:45
      • 4h 27m (1h 23m)
      • 1 Stop ORD · Chicago 1h 23m
      • United Airlines (UA 767)Airbus
        United Airlines (UA 1069)Boeing 737 Max 9 Passenger
      • United Airlines (UA 767)
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      • 18:18 IND
        22:45 TYS
        4Hrs, 27m 1 Stop (ORD)
      • INDIndianapolis Airport 18:18 - TYS 22:45 4h 27m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 18:18
        ORDChicago O'Hare International Airport 19:58
      • ORDChicago O'Hare International Airport 18:38
        TYSKnoxville Airport 22:45
      • 4h 27m (1h 20m)
      • 1 Stop ORD · Chicago 1h 20m
      • United Airlines (UA 3467)Embraer 170
        United Airlines (UA 1069)Boeing 737 800
      • United Airlines (UA 3467)
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      • 18:18 IND
        22:45 TYS
        4Hrs, 27m 1 Stop (ORD)
      • INDIndianapolis Airport 18:18 - TYS 22:45 4h 27m 1 Stop (ORD) Chicago
      • INDIndianapolis Airport 18:18
        ORDChicago O'Hare International Airport 19:58
      • ORDChicago O'Hare International Airport 18:35
        TYSKnoxville Airport 22:45
      • 4h 27m (1h 23m)
      • 1 Stop ORD · Chicago 1h 23m
      • United Airlines (UA 767)Airbus
        United Airlines (UA 1069)Boeing 737 800
      • United Airlines (UA 767)
        • M
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      No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
      How far is Knoxville from Indianapolis?

      The flight distance between Indianapolis and Knoxville is 467km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 05:40. The last flight of the day departs at 05:40. See the full list of flight times on Wego.

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